Just like anything, something can be over done. (Not referring to your 22" wheels, because I haven't seen them). But when you see a vehicle, that is practically all wheel, and can barely see the rubber, to me that is dumb.
And I have said it before, it bothers me when the vehicle comes OEM with really large rims, 20" for a Venza, give me a break. If you want to upgrade it fine, but the bigger Highlander doesn't even use 19".