Like someone mentioned, I think base IS250 RWD with some aftermarket work is a good choice.
Leather seats, maybe $1200-1500, throw in the heated seats while you're at it.
HIDs for $300.
Skip the sunroof.
Personally I'm okay with a good set of manual seat adjustments, as long as there is lumbar.
Mitlov: don't think you'd be happy with a slushbox
To say the least I had forgotten about that.
Hehe. I'm not really an enthusiast driver. My ideal, but nonexistent, car would be an MB E-Class Quattro designed, built, and backed by Toyota, with the exterior of a post-facelift E46, with the TL's active noise cancellation.