I'd get a VStrom for reliability, both the 650 and 1000 variants. There's also the Kawasaki Versys which is a little ugly. Honda NC700X is a little interesting, it's dubbed as having half a (Honda) Fit engine.
I'd consider a sport tourer as well, Honda ST1300, Yamaha FJR1300, Kawasaki Concours. All three will gobble up miles in comfort yet are still fun to ride.