Our 05' Ody EX has been great. It has had a few warranty issues, power steering pump, horn, rattles, windshield moldings...but it was a first year model. I love the way it drives and handles for a minivan, more so than the Sienna. The Odyssey has a more sporty feel compared to the Sienna, which is more soft.
But I do admit...the quality, especially the interior, isn't as good as previous Hondas I have owned. My 2001 Accord has better interior materials than my Odyssey.